发明名称 Oat extracts: refining, compositions and methods of use
摘要 A simple and efficient method for the production of stable, clear, high-potency oat extracts is disclosed. The method employs the use of differential dissociation constants and ultrafiltration to stabilise extracts, prevent hazing, and prevent the loss of functional activity as an anti-irritant and anti-oxidant. Also disclosed are compositions of oat extracts derived from whole oat grains and oatmeal. Further disclosed are compositions of oat extracts for use in cosmetic, nutraceutical, therapeutic medical and veterinary preparations.
申请公布号 US8815268(B2) 申请公布日期 2014.08.26
申请号 US201313958269 申请日期 2013.08.02
申请人 CEAPRO, Inc. 发明人 Redmond Mark J.;Fielder David A.
分类号 A61K31/196;A61K8/00;A61Q19/00;C07C229/62;A61K8/42 主分类号 A61K31/196
代理机构 Duane Morris LLP 代理人 Duane Morris LLP ;Steele, Jr. J. Rodman;Lefkowitz Gregory M.
主权项 1. A composition, comprising: an oat extract comprising, at least 1 ppm avenanthramide, andless than 0.01 wt-% proteins with a molecular weight greater than 10,000 Da; and at least one additional ingredient selected from the group consisting of alcohols, fats, oils, fatty acids, silicones, preservative, coloring agents, perfumes, and fragrances, wherein the oat extract is prepared by a method comprising: a. milling whole oats;b. extracting the resulting oatmeal with a solvent comprising water and a primary or a secondary alcohol;c. clarifying the extract by adjusting the pH of the resulting oat extract to <4.0;d. membrane filtration of the oat extract with a pH <4.0 through a membrane <104 MWCO.
地址 Edmonton, Alberta CA