| 发明名称 |
Modulation of immunity and CEACAM1 activity |
| 摘要 |
The present technology comprises methods for regulating an the immune system, and in particular methods for the regulation of a specific immune response, including the regulation of lymphocyte activity. Methods of the present technology comprise both the negative and positive modulation of CEACAM1 protein function. |
| 申请公布号 |
US8815248(B2) |
申请公布日期 |
2014.08.26 |
| 申请号 |
US200611423366 |
申请日期 |
2006.06.09 |
| 申请人 |
|
发明人 |
Markel Gal |
| 分类号 |
A61K39/00 |
主分类号 |
A61K39/00 |
| 代理机构 |
McAndrews, Held & Malloy, Ltd. |
代理人 |
McAndrews, Held & Malloy, Ltd. |
| 主权项 |
1. A method for enhancing natural killer-cell mediated killing activity, wherein said method comprises contacting a natural killer-cell expressing CEACAM1 with a CEACAM1 binding element that is a multimer agent comprising at least SEQ ID No. 1. |
| 地址 |
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