N-(imidazolidin-2-ylidene)quinoline derivatives as modulators of alpha 2 adrenergic receptors

摘要

The present invention relates to novel N-(imidazolidin-2-ylidene)quinoline derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals.

主权项

1. A compound of Formula I, an enantiomer, a diastereoisomer, a tautomer or a pharmaceutically acceptable salt thereof, wherein: R1 is hydrogen, substituted or unsubstituted C1-8 alkyl or halogen; Y is CH or N; X is CH or N; except compound N-(4,5-dihydro-1H-imidazol-2-yl)-3-quinolinamine.