| 发明名称 |
INDUCTION OF TUMOR IMMUNITY BY VARIANTS OF FOLATE BINDING PROTEIN |
| 摘要 |
The present invention is directed to variants of antigens comprising folate binding protein epitope (E39) as a composition associated with providing immunity against a tumor in an individual. The variant is effective in inducing cytotoxic T-lymphocytes but preferably not to the extent that they become sensitive to silencing by elimination, such as by apoptosis, or by anergy, as in unresponsiveness. |
| 申请公布号 |
PT2371854(E) |
申请公布日期 |
2014.08.25 |
| 申请号 |
PT20110004714T |
申请日期 |
2002.03.08 |
| 申请人 |
THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC.;BOARD OF REGENTS THE UNIVERSITY OF TEXAS SYSTEM |
发明人 |
GEORGE E. PEOPLES;CONSTANTIN G. IOANNIDES |
| 分类号 |
A61K9/12;C07K14/705;A61K9/72;A61K39/00;A61P35/00;C07K7/06;C07K14/47;C07K14/82 |
主分类号 |
A61K9/12 |
| 代理机构 |
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