发明名称 Compuestos derivados de sulfoxidos de 2-(piperidin-1-il)-dihidrotieno[3,2-d]pirimidina; metodo de preparacion; compuestos intermediarios; y uso para tratar enfermedades inflamatorias o alergicas tales como epoc y asma.
摘要 <p>The invention relates to novel piperidino-dihydrothienopyrimidine sulfoxides of formula I, wherein Ring A is a 6-membered aromatic ring which may optionally comprise one or two nitrogen atoms and wherein R is Cl and wherein R may be located either in the para-, meta- or ortho-position of Ring A, wherein S* is a sulphur atom that represents a chiral center, and all pharmaceutically acceptable salts, enantiomers and racemates, hydrates and solvates thereof and the use of these compounds for the treatment of inflammatory or allergic diseases of the respiratory tract such as COPD or asthma.</p>
申请公布号 CL2014000296(A1) 申请公布日期 2014.08.22
申请号 CL20140000296 申请日期 2014.02.06
申请人 BOEHRINGER INGELHEIM INTERNATIONAL GMBH. 发明人 WERTHMANN, ULRIKE;POUZET, PASCALE, A., J.;NICKOLAUS, PETER;FRUTOS, ROGELIO, P.;KIM, SOOJIN;MULDER,JASON, ALAN;PATEL, NITINCHANDRA;SENANAYAKE, CHRIS;TAMPONE, THOMAS, G.;YANG BING -SHIOU;WEI XUDONG
分类号 C07D401/04;A61K31/519;A61P29/00;C07D495/04 主分类号 C07D401/04
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