发明名称 Compuestos derivados de anillos de piridinas fusionados, inhibidores de btk; composicion farmaceutica; combinacion farmaceutica; y su uso para trastornos mediado por btk como artritis y sus variantes, trastornos hematologicos, enfermedad de crohn, entre otras.
摘要 The present invention relates to 6-5 membered fused pyridine ring compounds according to formula (I) or a pharmaceutically acceptable salt thereof or to pharmaceutical compositions comprising these compounds and to their use in therapy. In particular, the present invention relates to the use of 6-5 membered fused pyridine ring compounds according to formula I in the treatment of Brutons Tyrosine Kinase (Btk) mediated disorders.
申请公布号 CL2014000130(A1) 申请公布日期 2014.08.22
申请号 CL20140000130 申请日期 2014.01.17
申请人 MERCK SHARP & DOHME B.V. 发明人 BARF TJEERD A.;JANS CHRISTIAAN GERARDUS JOHANNES MARIA;MAN DE ADRIANUS PETRUS ANTONIUS;OUBRIE ARTHUR A;RAAIJMAKERS HANS C.A.;REWINKEL JOHANNES BERNARDUS MARIA;STERRENBURG JAN-GERARD;WIJKMANS JACOBUS C.H.M
分类号 C07D487/04;A61K31/4985;A61P19/08;A61P29/00;A61P31/00;A61P35/00;A61P37/00;C07D519/00 主分类号 C07D487/04
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