发明名称 |
Compuestos derivados de anillos de piridinas fusionados, inhibidores de btk; composicion farmaceutica; combinacion farmaceutica; y su uso para trastornos mediado por btk como artritis y sus variantes, trastornos hematologicos, enfermedad de crohn, entre otras. |
摘要 |
The present invention relates to 6-5 membered fused pyridine ring compounds according to formula (I) or a pharmaceutically acceptable salt thereof or to pharmaceutical compositions comprising these compounds and to their use in therapy. In particular, the present invention relates to the use of 6-5 membered fused pyridine ring compounds according to formula I in the treatment of Brutons Tyrosine Kinase (Btk) mediated disorders. |
申请公布号 |
CL2014000130(A1) |
申请公布日期 |
2014.08.22 |
申请号 |
CL20140000130 |
申请日期 |
2014.01.17 |
申请人 |
MERCK SHARP & DOHME B.V. |
发明人 |
BARF TJEERD A.;JANS CHRISTIAAN GERARDUS JOHANNES MARIA;MAN DE ADRIANUS PETRUS ANTONIUS;OUBRIE ARTHUR A;RAAIJMAKERS HANS C.A.;REWINKEL JOHANNES BERNARDUS MARIA;STERRENBURG JAN-GERARD;WIJKMANS JACOBUS C.H.M |
分类号 |
C07D487/04;A61K31/4985;A61P19/08;A61P29/00;A61P31/00;A61P35/00;A61P37/00;C07D519/00 |
主分类号 |
C07D487/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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