发明名称 |
ANTIGEN BINDING PROTEINS TO PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9 (PCSK9) |
摘要 |
Antigen binding proteins that interact with Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) are described. Methods of treating hypercholesterolemia and other disorders by administering a pharmaceutically effective amount of an antigen binding protein to PCSK9 are described. Methods of detecting the amount of PCSK9 in a sample using an antigen binding protein to PCSK9 are described. |
申请公布号 |
US2014235830(A1) |
申请公布日期 |
2014.08.21 |
申请号 |
US201414260975 |
申请日期 |
2014.04.24 |
申请人 |
Amgen, Inc. |
发明人 |
Jackson Simon Mark;Walker Nigel Pelham Clinton;Piper Derek Evan;Shen Wenyan;King Chadwick Terence;Ketchem Randal Robert;Mehlin Christopher;Carabeo Teresa Arazas |
分类号 |
C07K16/40 |
主分类号 |
C07K16/40 |
代理机构 |
|
代理人 |
|
主权项 |
1. (canceled) |
地址 |
Thousand Oaks CA US |