发明名称 ANTIGEN BINDING PROTEINS TO PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9 (PCSK9)
摘要 Antigen binding proteins that interact with Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) are described. Methods of treating hypercholesterolemia and other disorders by administering a pharmaceutically effective amount of an antigen binding protein to PCSK9 are described. Methods of detecting the amount of PCSK9 in a sample using an antigen binding protein to PCSK9 are described.
申请公布号 US2014235830(A1) 申请公布日期 2014.08.21
申请号 US201414260975 申请日期 2014.04.24
申请人 Amgen, Inc. 发明人 Jackson Simon Mark;Walker Nigel Pelham Clinton;Piper Derek Evan;Shen Wenyan;King Chadwick Terence;Ketchem Randal Robert;Mehlin Christopher;Carabeo Teresa Arazas
分类号 C07K16/40 主分类号 C07K16/40
代理机构 代理人
主权项 1. (canceled)
地址 Thousand Oaks CA US