| 发明名称 |
NOVEL ANTITHROMBOTIC AND ANTIATHEROSCLEROTIC AGENT AND METHOD FOR PRODUCING SAME (VARIANTS) |
| 摘要 |
The invention relates to the field of chemical and pharmaceutical industry and medicine and concerns compounds which can be used to produce agents for the treatment of cardiovascular diseases.;The use of 2-[2-cyano-2-[5-(hydroxymethyl)-3-methyl-1,3-oxazolidin-2-ylidene]ethylidene]indolin-3-one of formula I is proposed as a biologically active compound exhibiting the properties of exogenous nitric oxide donor, a platelet aggregation inhibitor, also exhibiting antihypertensive activity and activating activity towards the soluble guanylate cyclase enzyme. Variants of methods for synthesizing the above compound are also proposed.; |
| 申请公布号 |
US2014235868(A1) |
申请公布日期 |
2014.08.21 |
| 申请号 |
US201214344032 |
申请日期 |
2012.10.29 |
| 申请人 |
Proton OOO |
发明人 |
Ryabova Svetlana Yurevna;Parshin Valery Aleksandrovich;Granik Vladimir Grigorevich;Grank Vladimir Vladimirovich;Grigoriev Nikta Borisovich;Aleksseva Ludmila Mikhaylovna |
| 分类号 |
C07D413/06 |
主分类号 |
C07D413/06 |
| 代理机构 |
|
代理人 |
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| 主权项 |
1. The use of 2-[2-Cyano-2-[5-(hydroxymethyl)-3-methyl-1,3-oxazolidin-2-ylidene]ethylidene]indolin-3-one of formula I as a biologically active compound exhibiting the properties of exogenous nitric oxide donor, platelet aggregation inhibitor, also exhibiting antihypertensive activity and activating activity towards the soluble guanylate cyclase enzyme. |
| 地址 |
Tomsk RU |
