| 发明名称 |
METHODS AND COMPOSITIONS FOR MODULATING THE Wnt PATHWAY |
| 摘要 |
The invention provides methods and compositions for modulating the Wnt signaling pathway, in particular by interfering with binding of Dkk1 or SOST with LRP5 and/or LRP6. |
| 申请公布号 |
US2014235820(A1) |
申请公布日期 |
2014.08.21 |
| 申请号 |
US201414265170 |
申请日期 |
2014.04.29 |
| 申请人 |
Genentech, Inc. |
发明人 |
Bourhis Eric;Cochran Andrea;Zhang Yingnan |
| 分类号 |
C07K7/06;G01N33/92;C07K14/00;C07K7/64;C07K7/08 |
主分类号 |
C07K7/06 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. An isolated peptide comprising the amino acid sequence X0X1X2X3 where X0 is N; X1 is A, S, F, T, Y, L, or K, or R; X2 is I or V; and X3 is K, R, or H. |
| 地址 |
South San Francisco CA US |
