| 主权项 |
1. A compound represented by the formula (I-1): wherein R1 represents (1) a C1-8 alkyl group which may be substituted with 1 to 5 R21 group(s), (2) a C2-8 alkenyl group which may be substituted with 1 to 5 R21 group(s), (3) a C2-8 alkynyl group which may be substituted with 1 to 5 R21 group(s), (4) a C3-7 carbocycle which may be substituted with 1 to 5 substituent(s) selected from the group consisting of a C1-4 alkyl group, a C1-4 haloalkyl group, a C1-4 alkoxy group and a halogen atom, or (5) —CONR31R32; R21 represents (1) a halogen atom, (2) —OR22 (in the group, R22 represents (1) a hydrogen atom, (2) a C1-4 alkyl group or (3) a C1-4 haloalkyl group), (3) —NR23R24 (in the group, R23 and R24 each independently represent (1) a hydrogen atom or (2) a C1-4 alkyl group) or (4) an oxo group; R31 and R32 each independently represent (1) a hydrogen atom or (2) a C1-4 alkyl group; R2 represents (1) a hydrogen atom, (2) a C1-4 alkyl group or (3) a C1-4 haloalkyl group; R3 and R4 each independently represent (1) a halogen atom, (2) a C1-4 alkyl group, (3) a C1-4 haloalkyl group, (4) a C1-4 alkoxy group, (5) a hydroxy group, (6) -L-CONR6R7, (7) -L-SO2R8 or (8) -L-COOR9; R5 represents (1) a halogen atom, (2) a C1-4 alkyl group or (3) a C1-4 haloalkyl group; L represents (1) a bond, (2) a group represented by the formula:wherein A represents (1) a bond or (2) an oxygen atom; R12 and R13 each independently represent (1) a hydrogen atom, (2) a C1-4 alkyl group, (3) a hydroxy group or (4) NH2 or (5) R12 and R13 together with the carbon atom to which they are attached may form a C3-7 carbocycle; and the arrow on the right hand side binds to —CONR6R7, —SO2R8 or —COOR9, (3) a C2-4 alkenylene group, (4) a —O—C2-4 alkenylene group, (5) an oxygen atom or (6) a nitrogen atom which may be substituted with a C1-4 alkyl group;
R6 and R7 each independently represent (1) a hydrogen atom, (2) a C1-4 alkyl group, (3) a C1-4 haloalkyl group, (4) a hydroxy group, (5) —CONR15R16, (6) —SO2NR15R16, (7) —COR17 or (8) —SO2R17, or R6 and R7 together with the nitrogen atom to which they are attached may form a 4- to 7-membered nitrogen-containing saturated heterocycle that may be substituted with a hydroxy group; R8 represents (1) a C1-4 alkyl group, (2) a C1-4 haloalkyl group or (3) NR10R11; R9 represents (1) a hydrogen atom or (2) a C1-8 alkyl group; R10 and R11 each independently represent (1) a hydrogen atom, (2) a C1-4 alkyl group, (3) —CONR15R16, (4) —SO2NR15R16, COR17 or (6) —SO2R17; the ring 1 and the ring 2 each independently represent a 5- to 7-membered cyclic group; R14 represents (1) a hydrogen atom or (2) a hydroxy group; R15 and R16 each independently represent (1) a hydrogen atom, (2) a C1-4 alkyl group or (3) a 5- to 7-membered cyclic group; R17 represents (1) a C1-4 alkyl group or (2) a 5- to 7-membered cyclic group; M1 and M2 each independently represent (1) a bond, (2) —C(O)—, (3) —O—, (4) —S—, (5) —C(O)O—, (6) —CH2O— or (7) —C(O)NH—; n represents an integer of 1 to 2; m represents an integer of 1 to 2; p represents an integer of 0 to 5; q represents an integer of 0 to 5; r represents an integer of 0 to 4; t represents an integer of 1 to 4; when p is 2 or more, a plurality of R3 groups may be the same or different; when q is 2 or more, a plurality of R4 groups may be the same or different; when r is 2 or more, a plurality of R5 groups may be the same or different; and when t is 2 or more, a plurality of R12 and R13 groups may be respectively the same or different;a salt thereof, a solvate thereof, an N-oxide thereof or a prodrug thereof. |
