摘要 |
The present invention provides a novel nucleoside or nucleotide usable as a material for the synthesis of a nucleic acid medicine, particularly, a compound represented by formula (I) or a salt thereof [wherein: Y1 is CR6 or N; Y2 is CR7 or N; Y3 is CR8 or N; R6, R7 and R8 are each independently a hydrogen atom, halogen, cyano, a substituted or unsubstituted alkyl, or the like; Bx is a nucleic acid base moiety; Z1 and Z2 are each independently a hydrogen atom, a hydroxyl-protecting group or a reactive phosphorus group; R1 to R5 are each independently a hydrogen atom, halogen, cyano, a substituted or unsubstituted alkyl, or the like; and n is an integer of 0 to 3]. |