Closed Loop Control With Improved Alarm Functions

摘要

Methods, system and devices for monitoring control parameters in a closed loop control operation including continuously monitoring glucose level and automatic administration of a medication, detecting a condition associated with hypoglycemia, determining whether a probability of the detected condition associated with hypoglycemia exceeding a threshold level, and outputting a notification based upon the determination are provided.

主权项

1. A method, comprising:
determining a predictive glucose response based on prior monitored glucose sensor data and one or more exogenous factors; detecting a condition associated with hypoglycemia including determining a level of uncertainty in a monitored glucose level based on a predicted or anticipated glucose level; determining a probability that the detected condition associated with hypoglycemia corresponds to a hypoglycemic condition including whether glucose sensor data indicates a persistent low glucose level; comparing the determined probability that the detected condition associated with hypoglycemia corresponds to the hypoglycemic condition, to a probability threshold level to confirm a presence of the hypoglycemic condition; modifying a first medication delivery rate adjustment frequency to a second medication delivery rate adjustment frequency based on a variation in the monitored glucose level; and determining periodically at the second medication delivery rate adjustment frequency whether to adjust a medication delivery rate.