The invention encompasses a novel process for making piperidinone carboxamide indane and azainane derivatives, which are CGRP receptor antagonists useful for the treatment of migraine, utilizing a highly effective spiroacid synthesis.
申请公布号
AU2013232196(A1)
申请公布日期
2014.08.21
申请号
AU20130232196
申请日期
2013.03.13
申请人
MERCK SHARP & DOHME CORP.
发明人
BELYK, KEVIN M.;CLEATOR, EDWARD;KUO, SHEN-CHUN;MALIGRES, PETER EMMANUEL;XIANG, BANGPING;YASUDA, NOBUYOSHI;YIN, JIANGUO
