| 发明名称 |
PROCESS FOR PREPARING SAXAGLIPTIN AND ITS NOVEL INTERMEDIATES USEFUL IN THE SYNTHESIS THEREOF |
| 摘要 |
Methods of making saxagliptin, pharmaceutically acceptable salts and hydrates thereof and intermediates thereof. |
| 申请公布号 |
US2014235870(A1) |
申请公布日期 |
2014.08.21 |
| 申请号 |
US201414264770 |
申请日期 |
2014.04.29 |
| 申请人 |
Apicore, LLC |
发明人 |
Kovi Ravishanker;Rapole KeshavRao;Naik Ashish;Kannapan Jayaraman;Madala Muralikrishna;Thakor Sanjay |
| 分类号 |
C07D209/48;C07C45/30 |
主分类号 |
C07D209/48 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for making comprising the steps of treating adamantane 1-carboxylic acid with dimethyl sulfide and potassium carbonate to obtain treating the resulting compound with a reducing agent to obtainand
treating the resulting compound with triethylamine, dichloromethane, and oxalylchloride. |
| 地址 |
Somerset NJ US |
