发明名称 |
N-SUBSTITUTED HETEROCYCLIC DERIVATIVES AS KINASE INHIBITORS |
摘要 |
<p>The present invention provides N-substituted novel heterocyclic derivatives of formula (I) as protein kinase inhibitors, in which R1, R2 and 'n' have the same meanings given in the specification, and pharmaceutically acceptable salts thereof that are useful in the treatment and prevention in diseases or disorder, in particular their use in diseases or disorder where there is an advantage in inhibiting kinase enzyme, more particularly BTK enzyme. The present invention also provides methods for synthesizing and administering the kinase inhibitor compounds. The present invention also provides pharmaceutical formulations comprising at least one of the kinase inhibitor compounds together with a pharmaceutically acceptable carrier, diluent or excipient therefor.</p> |
申请公布号 |
WO2014125410(A1) |
申请公布日期 |
2014.08.21 |
申请号 |
WO2014IB58894 |
申请日期 |
2014.02.11 |
申请人 |
AURIGENE DISCOVERY TECHNOLOGIES LIMITED |
发明人 |
BORUAH, ANIMA;HOSAHALLI, SUBRAMANYA;PANIGRAHI, SUNIL KUMAR |
分类号 |
C07D221/02;C07D265/00;C07D295/00;C07D473/00 |
主分类号 |
C07D221/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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