发明名称 TRISUBSTITUTED HETEROCYCLIC DERIVATIVES AS ROR GAMMA MODULATORS
摘要 <p>The present invention provides trisubstituted heterocyclic derivatives of formula (I), which may be therapeutically useful, more particularly as RORγmodulators; (I) in which R1, R2, R3, Ra, X, L, m and ring A have the meanings given in the specification, and pharmaceutically acceptable salts thereof that are useful in the treatment and prevention of diseases or disorder, in particular their use in diseases or disorder where there is an advantage in modulating RORγreceptor. The present invention also provides preparation of the compounds and pharmaceutical formulations comprising at least one of the trisubstituted heterocyclic derivatives of formula (I) together with a pharmaceutically acceptable carrier, diluent or excipient therefor.</p>
申请公布号 WO2014125426(A1) 申请公布日期 2014.08.21
申请号 WO2014IB58957 申请日期 2014.02.13
申请人 AURIGENE DISCOVERY TECHNOLOGIES LIMITED 发明人 BEJUGAM, MALLESHAM;HOSAHALLI, SUBRAMANYA;MAHALINGAM, NATARAJAN
分类号 C07D213/75;A61K31/44;A61K31/495;A61P11/00;A61P17/00;C07D231/14;C07D401/04;C07D405/12 主分类号 C07D213/75
代理机构 代理人
主权项
地址