发明名称 Method for treatment of pulmonary fibrosis
摘要 Methods and compositions of the invention relate to the treatment of pulmonary fibrosis.
申请公布号 US2014235571(A1) 申请公布日期 2014.08.21
申请号 US201413999389 申请日期 2014.02.20
申请人 Galectin Therapeutics, Inc. 发明人 Traber Peter G.
分类号 A61K31/736 主分类号 A61K31/736
代理机构 代理人
主权项 1. A method comprising: a. obtaining a composition for parenteral or enteral administration comprising a galacto-rhamnogalacturonate in a pharmaceutical acceptable carrier, and b. administering to a subject in need thereof an effective dose of the composition that results in at least one of the following: at least 5% reduction of lung edema, at least 5% reduction of lung pathology severity scores associated with lung fibrosis, at least 5% reduction of lung tissue hydroxyproline accumulation, at least 5% reduction of expression of pro-inflammatory proteins, at least 5% reduction of expression of fibrogenic proteins, wherein the subject in need thereof has at least one of the following: a primary or secondary lung fibrotic disease.
地址 Norcross GA US