METHOD FOR ISOLATING SPECIFIC GENOMIC REGION USING MOLECULE BINDING SPECIFICALLY TO ENDOGENOUS DNA SEQUENCE

摘要

A method that comprises: (A) a step for fragmenting a genomic DNA that maintains an interaction state with a molecule under the interaction; and (B) a step for contacting the genomic DNA with a foreign molecule binding to a specific endogenous DNA sequence in the genomic DNA. According to this method, an arbitrary genomic region can be specifically isolated while maintaining an interaction state with a molecule under the interaction by using an endogenous DNA sequence within a target genomic region or the neighborhood thereof in a cell to be analyzed, without requiring a procedure for inserting a recognition sequence of a foreign DNA-binding molecule into the neighborhood of the target genomic region of the cell to be analyzed.