| 发明名称 |
Method for Secretory Production of Protein |
| 摘要 |
A novel technique for improving ability for secretory production of a multimeric protein of a coryneform bacterium is provided, and thereby a method for secretory production of a multimeric protein is provided. A multimeric protein is produced by secretory production utilizing a coryneform bacterium having an ability to produce a multimeric protein by secretory production and modified so that expression of a gene coding for a metallopeptidase is increased as an expression host. |
| 申请公布号 |
US2014234901(A1) |
申请公布日期 |
2014.08.21 |
| 申请号 |
US201414264600 |
申请日期 |
2014.04.29 |
| 申请人 |
AJINOMOTO CO., INC. |
发明人 |
Matsuda Yoshihiko;Beppu Haruki |
| 分类号 |
C12P21/00;C07K16/24;C07K14/475;C07K16/28 |
主分类号 |
C12P21/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A coryneform bacterium having an ability to produce a multimeric protein by secretory production, which is modified so that expression of a gene coding for a metallopeptidase is increased. |
| 地址 |
Tokyo JP |
