SETTING OF HARDENABLE BONE SUBSTITUTE

摘要

The invention relates to hardenabie ceramic bone substitute compositions having improved setting, powders for such compositions and methods for their manufacture and use in medical treatment. More specifically the invention relates to hardenable bone substitute powder and hardenabie bone substitute paste with improved setting properties, comprising calcium sulfate and heat-treated hydroxyapatite (passivated HA), which bone substitute is suitable for treatment of disorders of supportive tissue such as bone loss, bone fracture, bone trauma and osteomyelitis.

主权项

1. A hardenable bone substitute composition comprising:
a) a calcium sulfate hemihydrate; b) a passivated hydroxyapatite; c) an antimicrobial compound; and d) an aqueous liquid, wherein the setting times of the hardenable bone substitute composition are reduced compared to a composition with a), c), d), and a raw hydroxyapatite.