SUPER PARAMAGNETIC IRON OXIDE NANOPARTICLES WITH METALLIC COATINGS AND A METHOD OF SYHTHESIZING THE SAME

摘要

The various embodiments herein provide super paramagnetic iron oxide nanoparticles (SPIONs). The SPIONs have a plurality of metallic coatings and plurality of polymeric gaps. The embodiments herein also provide a method of synthesizing the SPIONs with metallic rings and polymeric gaps. The metallic coatings form a ring like structure on the outer surface of the SPION. The SPION has a size of 13 nm. The ring has a thickness of 2-3 nm. The rings are one or more in number. The polymeric gaps have a thickness of 3-5 nm. The polymeric gaps are one or more in number. The method involves mixing the SPIONs with a plurality of polymers and then forming a metallic ring on the outer surface of the SPIONs. The SPIONs have anti-bacterial properties and stop a growth of bacterial biofilms. The SPIONs also have SERS properties.

主权项

1. An engineered multimodal nanoparticle with anti-bacterial effect and theranosis application comprises:
a super paramagnetic iron oxide nanoparticle (SPION) with a plurality of metallic coatings and a plurality of polymeric gaps, and wherein one gap is made up of a plurality of polymeric molecules, wherein the coating has a thickness of 2-3 nm, and wherein the plurality of polymeric molecules is selected from a group consisting of carboxylated-dextran compound, ethanediyl bis(isonicotinate) compound, bis 2-((4-pyridinyl carbonyl)oxy)ethyl disulfide compound, poly-L-histidine compound and a combination thereof, and wherein the polymeric gap has a thickness of 3-5 nm, and wherein the nanoparticle has antibacterial property, wherein the nanoparticle stops a growth of a bacterial biofilm, wherein the nanoparticle is compatible with biological cells, and wherein the nanoparticle has Surface Enhanced Raman Scattering (SERS) properties.