COMPOSITIONS AND METHODS FOR DETECTING TLR3

摘要

The present invention relates to antibodies, antibody fragments, and derivatives thereof that specifically bind to TLR3 cell receptors present on the surface of cells. The invention also relates to hybridomas producing such antibodies; methods of making such antibodies; fragments, variants, and derivatives of the antibodies; pharmaceutical compositions comprising the same; methods of using the antibodies to detect TLR3 levels on the surface of cells, and the use of such antibodies and compositions for diagnostic or therapeutic purposes in subjects.

主权项

1. A method of producing an antibody that specifically binds a TLR3 polypeptide in paraffin-embedded tissue sections, said method comprising the steps of: a) immunizing a non-human mammal with an immunogen comprising a human TLR3 polypeptide; and b) preparing antibodies from said immunized animal that compete for binding to said TLR3 polypeptide with antibody 40F9.