发明名称 AGENT FOR INDUCING INTERFERON PRODUCTION CONTAINING LACTIC ACID BACTERIA
摘要 This invention provides an IFN inducer comprising, as an active ingredient, lactic acid bacteria and capable of inducing IFN production, an immunopotentiating agent or prophylactic agent against virus infection comprising such inducer, and a food or drink product comprising such IFN inducer and having IFN-inducing activity, immunopotentiating activity, or prophylactic activity against virus infection. The agent for inducing IFN production comprises, as active ingredients, lactic acid bacteria that can activate plasmacytoid dendritic cells (pDCs) and promote IFN production, such as Lactococcus garvieae NBRC100934, Lactococcus lactis subsp. cremoris JCM16167, Lactococcus lactis subsp. cremoris NBRC100676, Lactococcus lactis subsp. hordniae JCM1180, Lactococcus lactis subsp. hordniae JCM11040, Lactococcus lactis subsp. lactis NBRC12007, Lactococcus lactis subsp. lactis NRIC1150, Lactococcus lactis subsp. lactis JCM5805, Lactococcus lactis subsp. lactis JCM20101, Leuconostoc lactis NBRC12455, Leuconostoc lactis NRIC1540, Pediococcus damnosus JCM5886, or Streptococcus thermophilus TA-45.
申请公布号 US2014234379(A1) 申请公布日期 2014.08.21
申请号 US201414263306 申请日期 2014.04.28
申请人 KIRIN HOLDINGS KABUSHIKI KAISHA 发明人 Fujiwara Daisuke;JONAI Kenta;SUGIMURA Tetsu
分类号 A61K35/74 主分类号 A61K35/74
代理机构 代理人
主权项 1. A method for inducing IFN production in a subject, which comprises administering Lactococcus lactis JCM5805 or Lactococuss lactis JCM20101 capable of activating plasmacytoid dendritic cells (pDCs) and incuding IFN production or a cultured or processed product thereof to the subject.
地址 Tokyo JP