摘要 |
There is described a method (1) for making an array of micro-needles (16), comprising the steps of: - depositing (3) a plurality of drops (11) of a liquid substance comprising a polymer on a surface of a starting substrate ( 10 ); - positioning (4) a pyroelectric substrate (12) at a certain distance (D) from the starting substrate (10) in such a way that the drops (11) deposited are positioned between said surface (9) of the starting substrate (10) and a surface (14) of the pyroelectric substrate (12); varying the temperature (5) of the pyroelectric substrate (12) or a part thereof to induce on said surface (14) of the pyroelectric substrate (12) a charge density such that starting from the drops deposited (11), under the effect of an electrodynamic force, respective cones (13) are formed having a tip facing towards the pyroelectric substrate (12); - determining (6) a consolidation of the cones (13), to form said micro-needles, preventing the tip of said cones (13) from contacting said surfaces (14) of the pyroelectric substrate (12). |
申请人 |
CONSIGLIO NAZIONALE DELLE RICERCHE;FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA |
发明人 |
FERRARO, PIETRO;COPPOLA, SARA;FINIZIO, ANDREA;GRILLI, SIMONETTA;VESPINI, VERONICA;NETTI, PAOLO, ANTONIO;VECCHIONE, RAFFAELE;ESPOSITO, ELIANA |