| 摘要 |
<p>In order to more accurately evaluate the infiltration behavior of cancer cells under conditions approaching the environment in a living body than the prior art, a novel cell culture system, which is a three-dimensional environment and in which a plurality of types of cells co-exist, is constructed. For that purpose, a hydrogel substrate for cell evaluation, which is constituted by hydrogel and has a fiber- or sheet-like form, is used. The hydrogel substrate has a region (A) inside a cross section (S) in a plane perpendicular to a longitudinal axis, the periphery of which does not touch the periphery of the cross section (S) and which contains first cells. In addition, the region (A) is constituted by hydrogel with a low modulus of elasticity compared to a region (B) outside the region (A) in the cross section (S).</p> |
