发明名称 |
Compositions comprising NDGA derivatives and sorafenib and their use in treatment of cancer |
摘要 |
The present invention provides pharmaceutical compositions comprising derivatives of NDGA, including M4N (tetra-O-methyl nordihydroguaiaretic acid) and sorafenib and their use in the inhibition and treatment of neoplastic diseases, such as liver cancer, colon cancer, breast cancer, brain cancers and ovarian cancers, for example, in a subject. Compositions comprising derivatives of NDGA, including M4N, sorafenib and additional therapeutic agents are also provided. |
申请公布号 |
AU2013214731(A1) |
申请公布日期 |
2014.08.21 |
申请号 |
AU20130214731 |
申请日期 |
2013.02.04 |
申请人 |
CHUN, JONG;RULAND, CHRISTOPHER;HUANG, RU;THE JOHNS HOPKINS UNIVERSITY;LIANG, YU-CHUAN;MOLD, DAVID |
发明人 |
HUANG, RU CHIH;MOLD, DAVID;RULAND, CHRISTOPHER;LIANG, YU-CHUAN;CHUN, JONG HO |
分类号 |
A61K31/045;A61K31/03;A61K31/12;A61P35/00 |
主分类号 |
A61K31/045 |
代理机构 |
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代理人 |
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地址 |
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