发明名称 |
TETRANDRINE DERIVATIVES WITH SUBSTITUTED 5-CARBON, PREPARATION METHOD AND USE THEREOF |
摘要 |
<p>The present invention belongs to the field of natural medicine and pharmaceutical chemistry and specifically relates to novel 5-substituted tetrandrine derivatives of formula (I) and a pharmaceutically acceptable adduct, complex and salt thereof, to a process for the preparation of these compounds, pharmaceutical compositions containing such compounds and their use in preparing antineoplastic medicaments.</p> |
申请公布号 |
EP2767538(A1) |
申请公布日期 |
2014.08.20 |
申请号 |
EP20120825975 |
申请日期 |
2012.08.20 |
申请人 |
HANGZHOU BENSHENG PHARMACEUTICAL CO., LTD. |
发明人 |
XU, RONGZHEN;RONG, FRANK;XIE, FUWEN;LAI, HONGXI |
分类号 |
C07D491/147;A61K31/4748;A61P35/00;C07D491/18;C07D491/22 |
主分类号 |
C07D491/147 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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