发明名称 ARYLSULFONAMIDE-BASED MATRIX METALLOPROTEASE INHIBITORS
摘要 <p>The present invention provides a compound of formula (I): said compound is inhibitor of MMP-2, and/or MMP-8, and/or MMP-9, and/or MMP-12 and/or MMP-13, and thus can be employed for the treatment of a disorder or disease characterized by abnormal activity of MMP-2, and/or MMP-8, and/or MMP-9, and/or MMP-12 and/or MMP-13. Accordingly, the compound of formula (I) can be used in treatment of disorders or diseases mediated by MMP-2, and/or MMP-8, and/or MMP-9, and/or MMP-12, and/or MMP-13. Finally, the present invention also provides a pharmaceutical composition.</p>
申请公布号 EP2268612(B1) 申请公布日期 2014.08.20
申请号 EP20090724483 申请日期 2009.03.23
申请人 NOVARTIS AG 发明人 EHRHARDT, CLAUS;MCQUIRE, LESLIE WIGHTON;RIGOLLIER, PASCAL;ROGEL, OLIVIER;SHULTZ, MICHAEL;TOMMASI, RUBEN ALBERTO
分类号 C07C311/16;A61K31/18;A61P29/00;C07C317/24;C07C323/24;C07D207/20;C07D209/08;C07D211/24;C07D213/40;C07D235/06;C07D295/116;C07D333/18 主分类号 C07C311/16
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