发明名称 |
Therapeutic methods and compositions for solid delivery |
摘要 |
An administration device comprising an array of needles, one or more fluid agents, and at least one hydrogel is described. The device can simultaneously deliver a plurality of fluid agents along respective axes into a tissue. The use of hydrogel leads to constrained delivery of the fluid agents. The constrained delivery of an agent is also achieved by depositing a drug implant into a tissue. The effect of an agent on the tissue can be evaluated thereafter. In addition, the invention is directed to treating muscle diseases by delivering a therapeutic agent in vivo, and the use of reporter tissues for candidate drug evaluation, detecting and characterizing resistance. |
申请公布号 |
EP2767298(A2) |
申请公布日期 |
2014.08.20 |
申请号 |
EP20140166779 |
申请日期 |
2011.11.23 |
申请人 |
PRESAGE BIOSCIENCES, INC. |
发明人 |
KLINGHOFFER, RICHARD;FRAZIER, JASON;GRENLEY, MARC |
分类号 |
A61M5/142;A61M5/32 |
主分类号 |
A61M5/142 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|