发明名称 DI-AMINO-SUBSTITUTED HETEROCYCLIC COMPOUNDS AND METHODS OF USE
摘要 <p>The present invention comprises a new class of compounds capable of modulating the c-kit receptor and, accordingly, useful for treatment of c-kit mediated diseases, including various fibrotic and mast cell related diseases such as mastocytosis. The compounds have a general Formula I wherein R1-6, X and Y are defined herein. The invention further comprises pharmaceutical compositions, methods for treatment of c-kit mediated diseases, and intermediates and processes useful for the preparation of compounds of the invention.</p>
申请公布号 EP2057133(B1) 申请公布日期 2014.08.20
申请号 EP20070810613 申请日期 2007.07.17
申请人 AMGEN INC. 发明人 CHEN, NING;HU, ESSA
分类号 C07D261/20;A61K31/422;A61P37/00;C07D413/12;C07D413/14;C07D498/04 主分类号 C07D261/20
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