发明名称 METHOD FOR PRODUCTION OF ANTIBODY
摘要 The present invention provides a method of producing a recombinant antibody efficiently and at low cost. Disclosed is a method of producing an antibody or a fragment thereof, comprising allowing a cell to produce the antibody or the fragment, wherein the cell contains a larger number of copies of an exogenous DNA encoding the light chain or a fragment thereof of the antibody than the number of copies contained in the cell of an exogenous DNA encoding the heavy chain or a fragment thereof of the antibody. The present invention also provides a recombinant vector comprising one copy of a DNA encoding the heavy chain or a fragment thereof of an antibody and two or more copies of a DNA encoding the light chain or a fragment thereof of the antibody; and a transformant.
申请公布号 EP2202307(B1) 申请公布日期 2014.08.20
申请号 EP20080838661 申请日期 2008.10.14
申请人 CHUGAI SEIYAKU KABUSHIKI KAISHA 发明人 YAMADA, YOSHIKI;KIYASU, TATSUYA;TABATA, KAZUYUKI;KUZUMAKI, AKIHIRO;YAMASHIRO, MAI
分类号 C12N15/09;C12N5/10;C12P21/02 主分类号 C12N15/09
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