| 发明名称 |
SUBSTITUTED TETRAHYDROISOQUINOLINE COMPOUNDS AS FACTOR XIA INHIBITORS |
| 摘要 |
The present invention provides compounds of Formula (I) or stereoisomers, pharmaceutically acceptable salts thereof, wherein all of the variables are as defined herein. These compounds are inhibitors of factor XIa and/or plasma kallikrein which may be used as medicaments. |
| 申请公布号 |
EP2766347(A1) |
申请公布日期 |
2014.08.20 |
| 申请号 |
EP20120780357 |
申请日期 |
2012.10.12 |
| 申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
ORWAT, MICHAEL J.;PINTO, DONALD J.P.;SMITH II, LEON M.;SRIVASTAVA, SHEFALI |
| 分类号 |
C07D217/26;A61K31/4725;A61P7/02;C07D401/10;C07D401/12;C07D401/14;C07D405/14 |
主分类号 |
C07D217/26 |
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