发明名称 |
SILK FIBROIN-BASED MICRONEEDLES AND METHODS OF MAKING THE SAME |
摘要 |
A microneedle or microneedle device includes a microneedle body extending from a base to a penetrating tip formed from a silk fibroin based material, which is easy to fabricate and highly biocompatible. The microneedle device can include one or more microneedles mounted to a substrate. The silk fibroin can include active agents to be transported into or across biological barriers such as skin, tissue and cell membranes. The silk fibroin microneedles can be fully or partially biodegradable and/or bioerodible. The silk fibroin is highly stable, affords room temperature storage and is implantable. The silk fibroin structure can be modulated to control the rate of active agent delivery. |
申请公布号 |
EP2629836(A4) |
申请公布日期 |
2014.08.20 |
申请号 |
EP20110835053 |
申请日期 |
2011.10.19 |
申请人 |
TRUSTEES OF TUFTS COLLEGE |
发明人 |
KAPLAN, DAVID L.;TSIORIS, KONSTANTINOS;OMENETTO, FIORENZO G.;PRITCHARD, ELEANOR M. |
分类号 |
A61M37/00;A61B17/20;A61K9/00;A61K9/70;A61L27/00;A61L27/58;A61L31/12;A61M5/158 |
主分类号 |
A61M37/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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