| 发明名称 | Diagnostic antibody assay | ||
| 摘要 | Diagnostic assays for the diagnosis of amyloidosis, in particular Alzheimer's disease, and related aspects. In particular, monoclonal antibodies and an antibody assay are provided. | ||
| 申请公布号 | US8809508(B2) | 申请公布日期 | 2014.08.19 |
| 申请号 | US201213422583 | 申请日期 | 2012.03.16 |
| 申请人 | Probiodrug AG | 发明人 | Kleinschmidt Martin;Schilling Stephan;Rahfeld Jens-Ulrich;Ebermann Kristin;Demuth Hans-Ulrich |
| 分类号 | C07K16/18;C12N5/20 | 主分类号 | C07K16/18 |
| 代理机构 | Dentons US LLP | 代理人 | Dentons US LLP |
| 主权项 | 1. An isolated monoclonal antibody that binds to AβpGlu(11) peptides or variants thereof, wherein said antibody has a dissociation constant (KD) value of 10−7 M or less; and the variable part of the light chain of said antibody is encoded by a nucleic acid molecule having the nucleotide sequence of SEQ ID NO: 51 or has the amino acid sequence of SEQ ID NO: 52. | ||
| 地址 | Halle (Saale) DE | ||