Method for producing different populations of molecules or fine particles with arbitrary distribution forms and distribution densities simultaneously and in quantity, and masking member therefor

摘要

The formation in quantity of various different populations of a substance being studied with multiple combinations of distribution form and distribution density by dripping a suspension of a single concentration of the substance onto a masking member of a certain specified structure placed on a substrate by making use of the sedimentation of said substance.;A method to form populations of fine particles or molecules on a substrate by specifying the distribution form and distribution surface density, wherein a masking member provided with parallel through-holes and having a tilted wall structure to achieve the target distribution form and distribution density is prepared; a solution or a suspension of the substance being studied is dripped onto said masking member; and the substance settles through the region defined by the tilted wall structure of the masking member; and the result is that the substance settles along the tilted wall structure and passes through the region bounded by the upper boundary of said wall structure and deposits onto the substrate in the area bounded by the lower boundary of the wall structure.

主权项

1. A method for forming populations of fine particles or molecules on a substrate by specifying a distribution form and a distribution surface density, comprising: preparing a masking member comprising a tilted wall structure, wherein the tilted wall structure is designed to achieve a target distribution form and a target distribution density; positioning the masking member in close contact with a substrate; placing a solution or a suspension of the fine particles or molecules on the masking member; passing the substance through an upper region defined by an upper boundary of the tilted wall structure of the masking member; settling the substance along the tilted wall; depositing the substance onto the substrate in a predetermined area bounded by a lower boundary of the wall structure; and producing various different populations of molecules or particles with arbitrary distribution forms and distribution densities simultaneously and in quantity.