发明名称 |
Salts of benzimidazole compound and use thereof |
摘要 |
A sodium salt, magnesium salt, lithium salt, potassium salt, calcium salt or barium salt of (R)-2 -[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2 -pyridinyl]methyl]sulfinyl]-1H-benzimidazole, and a pharmaceutical composition comprising the salt. The novel salt is useful as an excellent antiulcer agent. |
申请公布号 |
US8809542(B2) |
申请公布日期 |
2014.08.19 |
申请号 |
US201313904609 |
申请日期 |
2013.05.29 |
申请人 |
Takeda Pharmaceutical Company Limited |
发明人 |
Kamiyama Keiji;Hashimoto Hideo |
分类号 |
C07D401/12 |
主分类号 |
C07D401/12 |
代理机构 |
Hamre, Schumann, Mueller & Larson. P.C. |
代理人 |
Hamre, Schumann, Mueller & Larson. P.C. |
主权项 |
1. A crystal of sodium salt of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole Monohydrate, wherein the X-ray diffraction spectrum have the following diffraction peaks:
(iii) 8.89, 8.47, 5.64, 5.24, 4.84, 4.23, 4.20, 4.09, 3.60, and 3.36 Angstrom. |
地址 |
Osaka JP |