Nanoshell therapy

摘要

Nano-constructs comprising nanoshells and methods of using the nano-constructs for treating or ameliorating a vascular condition are provided.

主权项

1. A method of treating or ameliorating a vascular condition, comprising:
(a) administering to a subject nano-constructs capable of absorbing energy from an electromagnetic radiation or energy from a fluctuating electromagnetic field and translating the energy into heat, (b) causing the nano-constructs to reach a target tissue wherein the nano-constructs reach the target tissue by extravasation through leaky vasculature in the target tissue or by targeting molecules on the surface of the nano-constructs that have affinity for the target tissue, and (c) applying an energy to the nano-constructs to cause the nano-constructs to heat the target tissue, wherein the nano-construct comprises a core material and a carbon or conducting polymer nanoshell formed on the core material.