发明名称 Use of metallocene compounds for cancer treatment
摘要 Metallocene compounds and pharmaceutical compositions containing these metallocene compounds are disclosed and described. Methods of treating cancer employing such metallocene compounds and pharmaceutical compositions also are provided.
申请公布号 US8809562(B2) 申请公布日期 2014.08.19
申请号 US201213488490 申请日期 2012.06.05
申请人 Chevron Phillips Chemical Company LP 发明人 Hlavinka Mark L.;Yang Qing;Murph Mandi Michelle
分类号 A61K31/28;A61K31/695;A61K31/7068;A61K31/135;A61K31/513;A61K38/21;A61K31/415;A61K45/06;A61K31/7135;A61K31/337 主分类号 A61K31/28
代理机构 Merchant & Gould P.C. 代理人 Merchant & Gould P.C.
主权项 1. A method of treating cancer in a subject in need thereof, comprising administering to the subject a composition comprising a therapeutically effective amount of a metallocene compound, and optionally a pharmaceutically acceptable diluent, excipient, or carrier; wherein the metallocene compound has the structure of formula CPH-1, CPH-2, CPH-3, CPH-4, CPH-5, CPH-6, CPH-7, CPH-8, CPH-9, CPH-10, CPH-11, CPH-12, CPH-13, CPH-14, or CPH-15, or a pharmaceutically acceptable salt thereof: wherein the cancer is melanoma, lung, colon, urinary bladder, breast, renal, prostate, ovarian, cervical, or head and neck cancer.
地址 The Woodlands TX US
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