发明名称 | Use of metallocene compounds for cancer treatment | ||
摘要 | Metallocene compounds and pharmaceutical compositions containing these metallocene compounds are disclosed and described. Methods of treating cancer employing such metallocene compounds and pharmaceutical compositions also are provided. | ||
申请公布号 | US8809562(B2) | 申请公布日期 | 2014.08.19 |
申请号 | US201213488490 | 申请日期 | 2012.06.05 |
申请人 | Chevron Phillips Chemical Company LP | 发明人 | Hlavinka Mark L.;Yang Qing;Murph Mandi Michelle |
分类号 | A61K31/28;A61K31/695;A61K31/7068;A61K31/135;A61K31/513;A61K38/21;A61K31/415;A61K45/06;A61K31/7135;A61K31/337 | 主分类号 | A61K31/28 |
代理机构 | Merchant & Gould P.C. | 代理人 | Merchant & Gould P.C. |
主权项 | 1. A method of treating cancer in a subject in need thereof, comprising administering to the subject a composition comprising a therapeutically effective amount of a metallocene compound, and optionally a pharmaceutically acceptable diluent, excipient, or carrier; wherein the metallocene compound has the structure of formula CPH-1, CPH-2, CPH-3, CPH-4, CPH-5, CPH-6, CPH-7, CPH-8, CPH-9, CPH-10, CPH-11, CPH-12, CPH-13, CPH-14, or CPH-15, or a pharmaceutically acceptable salt thereof: wherein the cancer is melanoma, lung, colon, urinary bladder, breast, renal, prostate, ovarian, cervical, or head and neck cancer. | ||
地址 | The Woodlands TX US |