发明名称 |
INIBIDORES DE PIM CINASE E MÉTODOS DE SEU USO |
摘要 |
New compounds, compositions and methods of inhibition of kinase activity associated with tumorigenesis in a human or animal subject are provided. In certain embodiments, the compounds and compositions are effective to inhibit the activity of at least one serine/threonine kinase or receptor tyrosine kinase. The new compounds and compositions may be used either alone or in combination with at least one additional agent for the treatment of a serine/threonine kinase- or receptor tyrosine kinase-mediated disorder, such as cancer. |
申请公布号 |
BRPI0808523(A2) |
申请公布日期 |
2014.08.19 |
申请号 |
BR2008PI08523 |
申请日期 |
2008.03.03 |
申请人 |
NOVARTIS VACCINES AND DIAGNOSTICS, INC. |
发明人 |
MATTHEW BURGER;MIKA LINDVALL;WOOSCOK HAN;JIONG LAN;GISELE NISHIGUCHI;CYNTHIA SHAFER;CORNELIA BELLAMACINA;KAY HUH;GORDANA ATALLAH;CHRISTOPHER MCBRIDE;WILLIAM ANTONIOS-MCCREA;TATIANA ZAVOROTINSKAYA;ANNETTE WALTER;PABLO GARCIA |
分类号 |
C07D213/78;A61K31/44;A61P35/00;C07D239/28;C07D401/12 |
主分类号 |
C07D213/78 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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