A NOVEL BENZOXAZINE BENZIMIDAZOLE DERIVATIVES, A PHARMACEUTICAL COMPOSITION COMPRISING THE SAME, AND A USE THEREOF

摘要

THE PRESENT INVENTION RELATES TO A NOVEL BENZOXAZINE BENZIMIDAZOLE DERIVATIVE OF FORMULA (1) AS AN ANTAGONIST AGAINST A VANILLOID RECEPTOR-1, A PHARMACEUTICAL COMPOSITION COMPRISING THE SAME AS AN ACTIVE INGREDIENT, AND A USE THEREOF. THE BENZOXAZINE BENZIMIDAZOLE DERIVATIVE OF THE PRESENT INVENTION MAY BE USEFUL FOR PREVENTING OR TREATING A DISEASE ASSOCIATED WITH ANTAGONISTIC ACTIVITY OF VANILLOID RECEPTOR-1: WHEREIN,R1,R2,R3,R3?,Q1,Q2,Q3, AND Q4 HAVE SAME MEANINGS AS DEFINED IN THE SPECIFICATION.