发明名称 |
GROUP A STREPTOCOCCAL M-RELATED PROTEINS AND METHODS OF USE |
摘要 |
Immunogenic group A streptococcus M-related polypeptides and peptides and immunogenic compositions comprising these M-related polypeptides and peptides are provided herein that evoke cross-opsonic and cross-protective anti-GAS and anti-SDSE antibodies in animals. Also provided are preparations comprising immunogenic compositions that comprise M-related polypeptides, peptides, or fusion proteins and that further comprise at least one additional group A streptococcus immunogen, such as an M peptide or Spa peptide. |
申请公布号 |
WO2014124446(A1) |
申请公布日期 |
2014.08.14 |
申请号 |
WO2014US15834 |
申请日期 |
2014.02.11 |
申请人 |
UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION |
发明人 |
DALE, JAMES, B.;COURTNEY, HARRY, S. |
分类号 |
A61K39/02;A61K39/002;A61K39/09 |
主分类号 |
A61K39/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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