主权项 |
1. A method for the purification of compounds of formula (I) wherein
R1 is Halogen or sulfonate,X is Fluorine atom (F),Y is CH2, CHD, or CD2, andD stands for Deuterium,comprising the step:
Purification of compound of formula (I) by distillation through at least one solid phase extraction (SPE) cartridge containing a stationary phase selected from the group comprising a C8 to C30 alkyl chain, more preferably a C8 to C20 alkyl chain, even more preferably a C15 to C20 alkyl chain, most preferred a C18 alkyl chain. |