DISSOLUBLE PDMS-MODIFIED p(HEMA-MAA) AMPHIPHILIC COPOLYMER AND METHOD FOR FABRICATING THE SAME

摘要

The present invention discloses a dissoluble PDMS-modified p(HEMA-MAA) amphiphilic copolymer and the method of fabricating the same. The amphiphilic copolymer of the present invention is fabricated via chemically bonding HEMA, MAA, and poly(dimethylsiloxane), bis(3-aminopropyl) terminated (PDMS) in aqueous solution. The PDMS-modified p(HEMA-MAA) amphiphilic copolymer can be dissolved completely in polar solvents, particularly alcohol solvents, to facilitate subsequent processing. The amphiphilic copolymer features adjustable hydrophobic-hydrophilic properties and exhibits excellent biocompatibility. Thus, it can be utilized in a number of advanced applications, including anti-fouling and drug delivery.

主权项

1. A dissoluble poly(dimethylsiloxane)-modified poly(2-hydroxyethyl methacrylate-methacrylic acid) amphiphilic copolymer, comprising compounds respectively expressed by Structural Formula I and Structural Formula II: and wherein m is an arbitrary integer of 1˜10, n is an arbitrary integer of 1˜40, x is an arbitrary integer of 1˜10, y is an arbitrary integer of 1˜10, and o is an arbitrary integer of 1˜10.