| 主权项 |
1. Compound of the general Formula I wherein A is a) Hydroxyl, b) branched or unbranched C1-C5 alkoxy, c) branched or unbranched Hydroxy C1-C5 Alkoxy, d) branched or unbranched O—C1-C5 Alkyl-(O—C1-C4 alkyl)n-O—C1-C4 alkyl, e) N(C1-C5 Alkyl)2, f) NH2, g) N(H)-L, h) O-L or i) O—Z, and G is a) Hydroxyl, b) O—Z b) branched or unbranched O—C1-C5 Alkyl, c) branched or unbranched O—C2-C5 Alkenyl, d) branched or unbranched O—C1-C5 Alkyl-(O—C1-C4 alkyl)n-O—C1-C4 alkyl or e) branched or unbranched O—C2-C5 Alkinyl, and R1 and/or R2, independently separate are a) Hydrogen, b) branched or unbranched 19F—C1-C10 Alkoxy, c) branched or unbranched 19F—C1-C10 Alkyl, d) branched or unbranched 19F—C2-C10 Alkenyl, e) branched or unbranched 19F—C2-C10 Alkinyl, f) substituted or unsubstituted 19F—C6-C10 mono- or bicyclic Aryl, g) substituted or unsubstituted 19F-alkyl-C6-C10 mono- or bicyclic Aryl h) substituted or unsubstituted 19F—C5-C10 mono- or bicyclic Heteroaryl, i) substituted or unsubstituted 19F-alkyl-C5-C10 mono- or bicyclic Heteroaryl j) substituted or unsubstituted 19F—C3-C6 Cyclo-Alkyl, k) substituted or unsubstituted 19F-alkyl-C3-C6 Cyclo-Alkyl l) Hydroxyl, m) branched or unbranched C1-C5 Alkyl or n) branched or unbranched C1-C5 Alkoxy wherein alkyl is optionally interrupted or is replaced by O, S or N, with the proviso that one of the substituent R1 or R2 comprises 19F atom and the other substituent comprises no 19F atom, and L is a) branched or unbranched C1-C5 Alkyl, b) branched or unbranched C2-C5 Alkenyl, c) branched or unbranched C1-C5 Alkyl-(O—C1-C4 alkyl)n-O—C1-C4 alkyl or d) branched or unbranched C2-C5 Alkinyl, and Z is a metal ion equivalent, with the meaning of n=0, 1, 2 or 3, and wherein mixtures of all possible diastereomers and/or enantiomers as well as enantiomerically pure compounds and pharmaceutical salts thereof are comprised. |
