发明名称 Scanning Suspension Comprising a Particle with a Diameter of at least 1 Micrometer
摘要 The invention provides a scanning suspension comprising a particle which is capable of at least in part disturbing a magnetic field, wherein said particle comprises a diameter of at least 1 μm, and use thereof for obtaining a scanning image. Preferably, said particle comprises holmium and a composition capable of essentially maintaining its structure during irradiation. A particle of the invention is suitable for preparing a kit of parts, comprising a diagnostic and a therapeutic composition which both comprise particles of the invention with essentially the same chemical structure, wherein said therapeutic composition is more radioactive than said diagnostic composition. Said kit of parts is especially suitable for treatment of a tumor. First, the distribution of a particle of the invention within an individual can be determined with a scanning image obtained with said scanning composition. Subsequently, a radioactive therapeutic composition can be administered, wherein a suitable dose of said therapeutic composition is derived from said scanning image.
申请公布号 US2014227177(A1) 申请公布日期 2014.08.14
申请号 US201314108567 申请日期 2013.12.17
申请人 Universiteit Utrecht Holding B.V. ;Universitair Medisch Centrum Utrecht 发明人 NIJSEN Johannes Franciscus Wilhelmus;VAN HET SCHIP Alfred Dirk;ZONNENBERG Bernard Antoni
分类号 A61K51/12;A61K33/24 主分类号 A61K51/12
代理机构 代理人
主权项 1. A kit of parts comprising a diagnostic composition and a therapeutic composition, said diagnostic composition and said therapeutic composition comprising particles with essentially the same chemical structure which are capable of at least in part disturbing a magnetic field, said therapeutic composition being more radioactive than said diagnostic composition.
地址 Utrecht NL