| 发明名称 |
AMINOPYRIMIDINE INHIBITORS OF TYROSINE KINASE |
| 摘要 |
The present invention relates to new aminopyrimidine inhibitors of tyrosine kinase activity, pharmaceutical compositions thereof, and methods of use thereof.; |
| 申请公布号 |
US2014227260(A1) |
申请公布日期 |
2014.08.14 |
| 申请号 |
US201414257347 |
申请日期 |
2014.04.21 |
| 申请人 |
Auspex Pharmaceuticals, Inc. |
发明人 |
Zhang Chengzhi |
| 分类号 |
C07D401/14;A61K45/06;A61K31/506 |
主分类号 |
C07D401/14 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A compound of structural Formula I: or a pharmaceutically acceptable salt thereof, wherein:
R1-R22 are independently selected from the group consisting of hydrogen and deuterium;at least one of R1-R22 is deuterium; andif R1-R3 are deuterium, then at least one of R4-R22 is deuterium. |
| 地址 |
La Jolla CA US |
