发明名称 |
DIAGNOSTIC USE OF PROSOMATOSTATIN |
摘要 |
The present invention relates to a method for the diagnosis, prognosis, monitoring and risk assessment of disturbances of the gastrointestinal tract activity and/or function and/or disturbances of the nutritional condition, with the exception of somatostatinoma, in a patient comprising the steps of: providing a sample of a bodily fluid of a patient; determining the level of proSomatostatin 1-64 or fragments thereof in said sample; correlating the level of proSomatostatin 1-64 or fragments thereof to the diagnosis, prognosis and risk assessment of disturbances of the gastrointestinal tract activity and/or function and/or disturbances of the nutritional condition, with the exception of somatostatinoma, in said patient, wherein said fragments have a length of at least 6 amino acid residues. The invention also relates to an antibody and a kit containing at least two antibodies. |
申请公布号 |
US2014227797(A1) |
申请公布日期 |
2014.08.14 |
申请号 |
US201214124180 |
申请日期 |
2012.05.31 |
申请人 |
Struck Joachim |
发明人 |
Struck Joachim |
分类号 |
G01N33/566;C07K16/26 |
主分类号 |
G01N33/566 |
代理机构 |
|
代理人 |
|
主权项 |
1. A method for the diagnosis, prognosis, monitoring and risk assessment of disturbances of the gastrointestinal tract activity and/or function and/or disturbances of the nutritional condition, with the exception of somatostatinoma, in a patient comprising the steps of:
i) providing a sample of a bodily fluid of a patient, ii) determining the level of proSomatostatin 1-64 (SEQ ID NO: 6) or fragments thereof in said sample, iii) correlating the level of proSomatostatin 1-64 (SEQ ID NO: 6) or fragments thereof to the diagnosis, prognosis and risk assessment of disturbances of the gastrointestinal tract activity and/or function and/or disturbances of the nutritional condition, with the exception of somatostatinoma, in said patient, wherein said fragments have a length of at least 6 amino acid residues. |
地址 |
Berlin DE |