主权项 |
1. A compound represented by Formula I, its enantiomers, diastereoisomers, tautomers or a pharmaceutically acceptable salt thereof, wherein: L is O, S, NH or CHR12; A is optionally substituted C6-10 aryl, optionally substituted heterocycle, optionally substituted C3-8 cycloalkyl or optionally substituted C5-8 cycloalkenyl; B is optionally substituted C8-10 aryl, optionally substituted heterocycle, optionally substituted C3-8 cycloalkyl or optionally substituted C5-8 cycloalkenyl; R1 is H, halogen, —OC1-3 alkyl, optionally substituted C1-3 alkyl, CN, C(O)R11, NO2, NR12R13 or hydroxyl; R2 is H, halogen, —OC1-3 alkyl, optionally substituted C1-3 alkyl, CN, C(O)R11, NO2, NR12R13 or hydroxyl; R3 is H, halogen, —OC1-3 alkyl, optionally substituted C1-3 alkyl, CN, C(O)R11, NO2, NR12R13 or hydroxyl; R4 is H, halogen, —OC1-3 alkyl, optionally substituted C1-3 alkyl, CN, C(O)R11, NR12R13 or hydroxyl; R5 is H, halogen, —OC1-3 alkyl, optionally substituted C1-3 alkyl, CN, C(O)R11, NR12R13 or hydroxyl; R6 is H, halogen, —OC1-3 alkyl, optionally substituted C1-3 alkyl, CN, C(O)R11, NR12R13 or hydroxyl; R7 is H, halogen, —OC1-3 alkyl, optionally substituted C1-3 alkyl, CN, C(O)R11, NR12R13 or hydroxyl; R8 is H, halogen, —OC1-3 alkyl, optionally substituted C1-3 alkyl, CN, C(O)R11, NR12R13 or hydroxyl; R9 is H, halogen, —OC1-3 alkyl, optionally substituted C1-3 alkyl, CN, C(O)R11, NR12R13 or hydroxyl; R10 is H, halogen, —OC1-3 alkyl, optionally substituted C1-3 alkyl, CN, C(O)R11, NR12R13 or hydroxyl; R11 is H, OH or C1-3 alkyl; R12 is H or C1-3 alkyl; and R13 is H or C1-3 alkyl. |