摘要 |
The present invention provides a composition containing 6-[N′-(3,4-dihydroxy-benzylidene)-hydrazino]-pyridine-3-sulfonic acid diethylamide as an active ingredient for skin whitening or a composition to prevent, treat, or alleviate hyperpigmented skin diseases. The composition of the present invention has excellent effects in skin whitening by inhibiting the migration of melanin by suppressing the binding between myosin 5a and melanophilin, which is a carrier of melanosome in melanocytes, and in preventing, alleviating, or treating pigmented skin diseases due to the excessive accumulation of melanin. |