发明名称 NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID
摘要 A compound that is effective as a diagnostic imaging probe that targets amyloid including is represented by the following formula (1), or salt thereof:;;wherein R1 is a radioactive halogen substituent, A1 and A2 independently represent CH or N. A diagnostic agent for Alzheimer's disease includes the compound represented by the above formula or a salt thereof. The above compound and the above diagnostic agent for Alzheimer's disease transfer into brain after administration, and indicate good accumulation on amyloid deposited in the brain.
申请公布号 US2014228569(A1) 申请公布日期 2014.08.14
申请号 US201214118317 申请日期 2012.05.18
申请人 Okumura Yuki;Maya Yoshifumi;Shoyama Yoshinari;Onishi Takako 发明人 Okumura Yuki;Maya Yoshifumi;Shoyama Yoshinari;Onishi Takako
分类号 A61K51/04;C07D471/04;C07F7/22 主分类号 A61K51/04
代理机构 代理人
主权项 1. A compound represented by the following formula (1), or a salt thereof: wherein R1 is a radioactive halogen substituent, and A1 and A2 independently represent CH or N.
地址 Chiba JP