发明名称 |
NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID |
摘要 |
A compound that is effective as a diagnostic imaging probe that targets amyloid including is represented by the following formula (1), or salt thereof:;;wherein R1 is a radioactive halogen substituent, A1 and A2 independently represent CH or N. A diagnostic agent for Alzheimer's disease includes the compound represented by the above formula or a salt thereof. The above compound and the above diagnostic agent for Alzheimer's disease transfer into brain after administration, and indicate good accumulation on amyloid deposited in the brain. |
申请公布号 |
US2014228569(A1) |
申请公布日期 |
2014.08.14 |
申请号 |
US201214118317 |
申请日期 |
2012.05.18 |
申请人 |
Okumura Yuki;Maya Yoshifumi;Shoyama Yoshinari;Onishi Takako |
发明人 |
Okumura Yuki;Maya Yoshifumi;Shoyama Yoshinari;Onishi Takako |
分类号 |
A61K51/04;C07D471/04;C07F7/22 |
主分类号 |
A61K51/04 |
代理机构 |
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代理人 |
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主权项 |
1. A compound represented by the following formula (1), or a salt thereof: wherein R1 is a radioactive halogen substituent, and A1 and A2 independently represent CH or N. |
地址 |
Chiba JP |